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Hypersensitivity to valsartan, hydrochlorothiazide, other sulfonamide-derived medicinal products or to any of the excipients.
Second and third trimester of pregnancy (see Precautions and Use in Pregnancy & Lactation).
Severe hepatic impairment, biliary cirrhosis and cholestasis.
Severe renal impairment (creatinine clearance <30 ml/min, anuria.
Refractory hypokalaemia, hyponatraemia, hypercalcaemia, and symptomatic hyperuricaemia.
The concomitant use of Valsartan HCT with aliskiren-containing products is contraindicated in patients with diabetes mellitus or renal impairment (GFR <60 ml/min/1.73 m2).
